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Re-positive coronavirus disease 2019 PCR test: could it be a reinfection?
The coronavirus disease 2019 (COVID-19) outbreak started in December 2019 and rapidly spread around the globe as a major health threat. Several reports on re-positive cases subsequent to discharge from hospitals caught our attention. We aimed to highlight RT-qPCR positivity re-detection after discha...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439804/ https://www.ncbi.nlm.nih.gov/pubmed/32843984 http://dx.doi.org/10.1016/j.nmni.2020.100748 |
Sumario: | The coronavirus disease 2019 (COVID-19) outbreak started in December 2019 and rapidly spread around the globe as a major health threat. Several reports on re-positive cases subsequent to discharge from hospitals caught our attention. We aimed to highlight RT-qPCR positivity re-detection after discharge from isolation, with special consideration of the possible reasons behind it. We found that re-positive RT-qPCR assays for severe acute respiratory syndrome coronavirus 2 after previous negative results might be attributed to false-negative laboratory results and prolonged viral shedding, rather than to re-infection. These findings are encouraging and should be validated in a larger cohort. |
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