Cargando…

Lactoferrin is a dynamic protein in human melioidosis and is a TLR4-dependent driver of TNF-α release in Burkholderia thailandensis infection in vitro

Melioidosis is an often-severe tropical infection caused by Burkholderia pseudomallei (Bp) with high associated morbidity and mortality. Burkholderia thailandensis (Bt) is a closely related surrogate that does not require BSL-3 conditions for study. Lactoferrin is an iron-binding glycoprotein that c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wright, Shelton W., Lovelace-Macon, Lara, Ducken, Deirdre, Tandhavanant, Sarunporn, Teparrukkul, Prapit, Hantrakun, Viriya, Limmathurotsakul, Direk, Chantratita, Narisara, West, T. Eoin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439809/ https://www.ncbi.nlm.nih.gov/pubmed/32764765 http://dx.doi.org/10.1371/journal.pntd.0008495

Ejemplares similares

Exonic sequencing identifies TLR1 genetic variation associated with mortality in Thais with melioidosis
por: Wright, Shelton W., et al.
Publicado: (2019)

A 2-Biomarker Model Augments Clinical Prediction of Mortality in Melioidosis
por: Wright, Shelton W, et al.
Publicado: (2020)

Human Immune Responses to Melioidosis and Cross-Reactivity to Low-Virulence Burkholderia Species, Thailand
por: Rongkard, Patpong, et al.
Publicado: (2020)

Competition between Burkholderia pseudomallei and B. thailandensis
por: Ngamdee, Wikanda, et al.
Publicado: (2015)

sTREM-1 predicts mortality in hospitalized patients with infection in a tropical, middle-income country
por: Wright, Shelton W., et al.
Publicado: (2020)

Flagellin-independent effects of a Toll-like receptor 5 polymorphism in the inflammatory response to Burkholderia pseudomallei
por: Dickey, Amy K., et al.
Publicado: (2019)

Sensitivity and specificity of a lateral flow immunoassay (LFI) in serum samples for diagnosis of melioidosis
por: Wongsuvan, Gumphol, et al.
Publicado: (2018)

IL-1R2-based biomarker models predict melioidosis mortality independent of clinical data
por: Kaewarpai, Taniya, et al.
Publicado: (2023)

Serum From Melioidosis Survivors Diminished Intracellular Burkholderia pseudomallei Growth in Macrophages: A Brief Research Report
por: Chaichana, Panjaporn, et al.
Publicado: (2020)

Common TLR1 Genetic Variation Is Not Associated with Death from Melioidosis, a Common Cause of Sepsis in Rural Thailand
por: Chantratita, Narisara, et al.
Publicado: (2014)

Role of Burkholderia pseudomallei–Specific IgG2 in Adults with Acute Melioidosis, Thailand
por: Chaichana, Panjaporn, et al.
Publicado: (2021)

Management and outcomes of severe dengue patients presenting with sepsis in a tropical country
por: Teparrukkul, Prapit, et al.
Publicado: (2017)

Evaluation of a Latex Agglutination Assay for the Identification of Burkholderia pseudomallei and Burkholderia mallei
por: Duval, Brea D., et al.
Publicado: (2014)

Comparative clinical characteristics and outcomes of patients with community acquired bacteremia caused by Escherichia coli, Burkholderia pseudomallei and Staphylococcus aureus: A prospective observational study (Ubon-sepsis)
por: Somayaji, Ranjani, et al.
Publicado: (2021)

Presence of B. thailandensis and B. thailandensis expressing B. pseudomallei-like capsular polysaccharide in Thailand, and their associations with serological response to B. pseudomallei
por: Hantrakun, Viriya, et al.
Publicado: (2018)

Effect of colony morphology variation of Burkholderia pseudomallei on intracellular survival and resistance to antimicrobial environments in human macrophages in vitro
por: Tandhavanant, Sarunporn, et al.
Publicado: (2010)

Monoclonal Antibody-Based Immunofluorescence Microscopy for the Rapid Identification of Burkholderia pseudomallei in Clinical Specimens
por: Tandhavanant, Sarunporn, et al.
Publicado: (2013)

Rapid Detection of Burkholderia pseudomallei in Blood Cultures Using a Monoclonal Antibody-Based Immunofluorescent Assay
por: Chantratita, Narisara, et al.
Publicado: (2013)

Clinical epidemiology and outcomes of community acquired infection and sepsis among hospitalized patients in a resource limited setting in Northeast Thailand: A prospective observational study (Ubon-sepsis)
por: Hantrakun, Viriya, et al.
Publicado: (2018)

Evaluation of antigen-detecting and antibody-detecting diagnostic test combinations for diagnosing melioidosis
por: Amornchai, Premjit, et al.
Publicado: (2021)

A nonsense mutation in TLR5 is associated with survival and reduced IL-10 and TNF-α levels in human melioidosis
por: Chaichana, Panjaporn, et al.
Publicado: (2017)

Gastrointestinal tract involvement in melioidosis
por: Teparrukkul, Prapit, et al.
Publicado: (2017)

Enhanced bedside mortality prediction combining point-of-care lactate and the quick Sequential Organ Failure Assessment (qSOFA) score in patients hospitalised with suspected infection in southeast Asia: a cohort study
por: Wright, Shelton W, et al.
Publicado: (2022)

Utility of qSOFA and modified SOFA in severe malaria presenting as sepsis
por: Teparrukkul, Prapit, et al.
Publicado: (2019)

T-Cell Responses Are Associated with Survival in Acute Melioidosis Patients
por: Jenjaroen, Kemajittra, et al.
Publicado: (2015)

Human Infection with Burkholderia thailandensis, China, 2013
por: Dance, David A.B., et al.
Publicado: (2018)

Melioidosis Caused by Burkholderia pseudomallei in Drinking Water, Thailand, 2012
por: Limmathurotsakul, Direk, et al.
Publicado: (2014)

Clinical Epidemiology of Septic Arthritis Caused by Burkholderia pseudomallei and Other Bacterial Pathogens in Northeast Thailand
por: Teparrukkul, Prapit, et al.
Publicado: (2017)

Screen of whole blood responses to flagellin identifies TLR5 variation associated with outcome in melioidosis
por: Chantratita, Narisara, et al.
Publicado: (2013)

Antibodies in Melioidosis: The Role of the Indirect Hemagglutination Assay in Evaluating Patients and Exposed Populations
por: Chaichana, Panjaporn, et al.
Publicado: (2018)

Infection with Burkholderia pseudomallei – immune correlates of survival in acute melioidosis
por: Dunachie, Susanna J., et al.
Publicado: (2017)

Early management of sepsis in medical patients in rural Thailand: a single-center prospective observational study
por: Rudd, Kristina E., et al.
Publicado: (2019)

Sensitivity and specificity of DPP(®) Fever Panel II Asia in the diagnosis of malaria, dengue and melioidosis
por: Amornchai, Premjit, et al.
Publicado: (2022)

Genomic loss in environmental and isogenic morphotype isolates of Burkholderia pseudomallei is associated with intracellular survival and plaque-forming efficiency
por: Saiprom, Natnaree, et al.
Publicado: (2020)

Proteomic analysis of colony morphology variants of Burkholderia pseudomallei defines a role for the arginine deiminase system in bacterial survival
por: Chantratita, Narisara, et al.
Publicado: (2012)

Effectiveness of a multifaceted prevention programme for melioidosis in diabetics (PREMEL): A stepped-wedge cluster-randomised controlled trial
por: Suntornsut, Pornpan, et al.
Publicado: (2021)

NLRC4 and TLR5 Each Contribute to Host Defense in Respiratory Melioidosis
por: West, T. Eoin, et al.
Publicado: (2014)

Toll-Like Receptor 4 Region Genetic Variants are Associated with Susceptibility to Melioidosis
por: West, T. Eoin, et al.
Publicado: (2011)

Genomic patterns of pathogen evolution revealed by comparison of Burkholderia pseudomallei, the causative agent of melioidosis, to avirulent Burkholderia thailandensis
por: Yu, Yiting, et al.
Publicado: (2006)

Fatal Melioidosis in Goats in Bangkok, Thailand
por: Tonpitak, Walaiporn, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_7uo2v739gihmb795mguamtp2q4