Therapeutic vascular growth in the heart

Despite tremendous efforts in preclinical research over the last decades, the clinical translation of therapeutic angiogenesis to grow stable and functional blood vessels in patients with ischemic diseases continues to prove challenging. In this mini review, we briefly present the current main appro...

Descripción completa

Detalles Bibliográficos
Autores principales: Brakenhielm, Ebba, Richard, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2019
Materias:
Mini Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439849/
https://www.ncbi.nlm.nih.gov/pubmed/32923948
http://dx.doi.org/10.1530/VB-19-0006
_version_ 1783573062471385088
author Brakenhielm, Ebba
Richard, Vincent
author_facet Brakenhielm, Ebba
Richard, Vincent
author_sort Brakenhielm, Ebba
collection PubMed
description Despite tremendous efforts in preclinical research over the last decades, the clinical translation of therapeutic angiogenesis to grow stable and functional blood vessels in patients with ischemic diseases continues to prove challenging. In this mini review, we briefly present the current main approaches applied to improve pro-angiogenic therapies. Specific examples from research on therapeutic cardiac angiogenesis and arteriogenesis will be discussed, and finally some suggestions for future therapeutic developments will be presented.
format Online
Article
Text
id pubmed-7439849
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Bioscientifica Ltd
record_format MEDLINE/PubMed
spelling pubmed-74398492020-09-10 Therapeutic vascular growth in the heart Brakenhielm, Ebba Richard, Vincent Vasc Biol Mini Review Despite tremendous efforts in preclinical research over the last decades, the clinical translation of therapeutic angiogenesis to grow stable and functional blood vessels in patients with ischemic diseases continues to prove challenging. In this mini review, we briefly present the current main approaches applied to improve pro-angiogenic therapies. Specific examples from research on therapeutic cardiac angiogenesis and arteriogenesis will be discussed, and finally some suggestions for future therapeutic developments will be presented. Bioscientifica Ltd 2019-03-28 /pmc/articles/PMC7439849/ /pubmed/32923948 http://dx.doi.org/10.1530/VB-19-0006 Text en © 2019 The authors http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/) .
spellingShingle Mini Review
Brakenhielm, Ebba
Richard, Vincent
Therapeutic vascular growth in the heart
title Therapeutic vascular growth in the heart
title_full Therapeutic vascular growth in the heart
title_fullStr Therapeutic vascular growth in the heart
title_full_unstemmed Therapeutic vascular growth in the heart
title_short Therapeutic vascular growth in the heart
title_sort therapeutic vascular growth in the heart
topic Mini Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439849/
https://www.ncbi.nlm.nih.gov/pubmed/32923948
http://dx.doi.org/10.1530/VB-19-0006
work_keys_str_mv AT brakenhielmebba therapeuticvasculargrowthintheheart
AT richardvincent therapeuticvasculargrowthintheheart

Ejemplares similares