Ghrelin and vascular protection

Ghrelin is a small peptide with important roles in the regulation of appetite, gut motility, glucose homeostasis as well as cardiovascular protection. This review highlights the role that acyl ghrelin plays in maintaining normal endothelial function by maintaining the balance of vasodilator-vasocons...

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Detalles Bibliográficos
Autores principales: Pearson, James T, Shirai, Mikiyasu, Sukumaran, Vijayakumar, Du, Cheng-Kun, Tsuchimochi, Hirotsugu, Sonobe, Takashi, Waddingham, Mark T, Katare, Rajesh, Schwenke, Daryl O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2019
Materias:
Mini Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439925/
https://www.ncbi.nlm.nih.gov/pubmed/32923960
http://dx.doi.org/10.1530/VB-19-0024
Descripción
Sumario:Ghrelin is a small peptide with important roles in the regulation of appetite, gut motility, glucose homeostasis as well as cardiovascular protection. This review highlights the role that acyl ghrelin plays in maintaining normal endothelial function by maintaining the balance of vasodilator-vasoconstrictor factors, inhibiting inflammatory cytokine production and immune cell recruitment to sites of vascular injury and by promoting angiogenesis.

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