Metformin Preconditioning Improves Hepatobiliary Function and Reduces Injury in a Rat Model of Normothermic Machine Perfusion and Orthotopic Transplantation

BACKGROUND. Preconditioning of donor livers before organ retrieval may improve organ quality after transplantation. We investigated whether preconditioning with metformin reduces preservation injury and improves hepatobiliary function in rat donor livers during ex situ normothermic machine perfusion...

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Detalles Bibliográficos
Autores principales: Westerkamp, Andrie C., Fujiyoshi, Masato, Ottens, Petra J., Nijsten, Maarten W.N., Touw, Daan J., de Meijer, Vincent E., Lisman, Ton, Leuvenink, Henri G.D., Moshage, Han, Berendsen, Tim A., Porte, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Original Basic Science—Liver
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439933/
https://www.ncbi.nlm.nih.gov/pubmed/32150043
http://dx.doi.org/10.1097/TP.0000000000003216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439933/
https://www.ncbi.nlm.nih.gov/pubmed/32150043
http://dx.doi.org/10.1097/TP.0000000000003216

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