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Ultrasound and radiological features of abdominal unicentric castleman's disease: A case series study
This study aimed to improve the diagnostic accuracy of abdominal unicentric Castleman's disease (UCD) by retrospectively summarizes the relatively specific imaging features of UCD. This study retrospectively collected fifteen patients with abdominal UCD confirmed by pathology. All patients were...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440244/ https://www.ncbi.nlm.nih.gov/pubmed/32358399 http://dx.doi.org/10.1097/MD.0000000000020102 |
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author | Lv, Kun Zhao, Yanan Xu, Wen Zhang, Chao Huang, Pintong |
author_facet | Lv, Kun Zhao, Yanan Xu, Wen Zhang, Chao Huang, Pintong |
author_sort | Lv, Kun |
collection | PubMed |
description | This study aimed to improve the diagnostic accuracy of abdominal unicentric Castleman's disease (UCD) by retrospectively summarizes the relatively specific imaging features of UCD. This study retrospectively collected fifteen patients with abdominal UCD confirmed by pathology. All patients were underwent ultrasound (US), computed tomography (CT), or magnetic resonance imaging (MRI) examination. The imaging findings of UCDs were analyzed by senior radiologists. Fifteen patients included 7 males and 8 females, aged 30 to 68 years old, with an average age of 51.73 ± 13.57. In the 15 cases, 7 were located around the mesentery, 4 were located in the retroperitoneal space, and 4 in the liver. Fifteen cases contained solid masses, of which 13 had clear margins and 2 had blurred margins. The size of the mass ranged from 1.5 to 14.2 cm, with an average of 6.49 ± 4.16 cm. US showed that 9 lesions were presented with hypo-echogenicity while 5 lesions presented with hyper-echogenicity spots. Unenhanced CT showed that the lesions were comprised of soft tissue while calcified lesions were found in 10 of the cases (66.67%, 10/15). T1-weighted imaging (T1WI) suggested the lesions as iso/hypo-signal, and mildly hyper-signal on T2-weighted imaging (T2WI). Diffusion-weighted imaging (DWI) showed different degrees of hyper-signal. Contrast-enhanced US and CT/MRI showed obvious enhancement at the arterial phase in 12 cases (85.71%, 12/14), most of which (50%, 7/14) showed continuous enhancement at the delayed phase. Feeding vessel could be seen within, or around the lesion in 5 cases (35.71%, 5/14). The study suggests that abdominal UCD commonly manifests as well-defined, homogeneous, solid, and hypervascular masses. Calcification and the presence of feeding vessel in the tumors are relatively specific features of abdominal UCD. |
format | Online Article Text |
id | pubmed-7440244 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-74402442020-09-04 Ultrasound and radiological features of abdominal unicentric castleman's disease: A case series study Lv, Kun Zhao, Yanan Xu, Wen Zhang, Chao Huang, Pintong Medicine (Baltimore) 6800 This study aimed to improve the diagnostic accuracy of abdominal unicentric Castleman's disease (UCD) by retrospectively summarizes the relatively specific imaging features of UCD. This study retrospectively collected fifteen patients with abdominal UCD confirmed by pathology. All patients were underwent ultrasound (US), computed tomography (CT), or magnetic resonance imaging (MRI) examination. The imaging findings of UCDs were analyzed by senior radiologists. Fifteen patients included 7 males and 8 females, aged 30 to 68 years old, with an average age of 51.73 ± 13.57. In the 15 cases, 7 were located around the mesentery, 4 were located in the retroperitoneal space, and 4 in the liver. Fifteen cases contained solid masses, of which 13 had clear margins and 2 had blurred margins. The size of the mass ranged from 1.5 to 14.2 cm, with an average of 6.49 ± 4.16 cm. US showed that 9 lesions were presented with hypo-echogenicity while 5 lesions presented with hyper-echogenicity spots. Unenhanced CT showed that the lesions were comprised of soft tissue while calcified lesions were found in 10 of the cases (66.67%, 10/15). T1-weighted imaging (T1WI) suggested the lesions as iso/hypo-signal, and mildly hyper-signal on T2-weighted imaging (T2WI). Diffusion-weighted imaging (DWI) showed different degrees of hyper-signal. Contrast-enhanced US and CT/MRI showed obvious enhancement at the arterial phase in 12 cases (85.71%, 12/14), most of which (50%, 7/14) showed continuous enhancement at the delayed phase. Feeding vessel could be seen within, or around the lesion in 5 cases (35.71%, 5/14). The study suggests that abdominal UCD commonly manifests as well-defined, homogeneous, solid, and hypervascular masses. Calcification and the presence of feeding vessel in the tumors are relatively specific features of abdominal UCD. Wolters Kluwer Health 2020-05-01 /pmc/articles/PMC7440244/ /pubmed/32358399 http://dx.doi.org/10.1097/MD.0000000000020102 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 |
spellingShingle | 6800 Lv, Kun Zhao, Yanan Xu, Wen Zhang, Chao Huang, Pintong Ultrasound and radiological features of abdominal unicentric castleman's disease: A case series study |
title | Ultrasound and radiological features of abdominal unicentric castleman's disease: A case series study |
title_full | Ultrasound and radiological features of abdominal unicentric castleman's disease: A case series study |
title_fullStr | Ultrasound and radiological features of abdominal unicentric castleman's disease: A case series study |
title_full_unstemmed | Ultrasound and radiological features of abdominal unicentric castleman's disease: A case series study |
title_short | Ultrasound and radiological features of abdominal unicentric castleman's disease: A case series study |
title_sort | ultrasound and radiological features of abdominal unicentric castleman's disease: a case series study |
topic | 6800 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440244/ https://www.ncbi.nlm.nih.gov/pubmed/32358399 http://dx.doi.org/10.1097/MD.0000000000020102 |
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