GFAP at 50

Fifty years have passed since the discovery of glial fibrillary acidic protein (GFAP) by Lawrence Eng and colleagues. Now recognized as a member of the intermediate filament family of proteins, it has become a subject for study in fields as diverse as structural biology, cell biology, gene expressio...

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Detalles Bibliográficos
Autores principales: Messing, Albee, Brenner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440737/
https://www.ncbi.nlm.nih.gov/pubmed/32811163
http://dx.doi.org/10.1177/1759091420949680
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author Messing, Albee
Brenner, Michael
author_facet Messing, Albee
Brenner, Michael
author_sort Messing, Albee
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description Fifty years have passed since the discovery of glial fibrillary acidic protein (GFAP) by Lawrence Eng and colleagues. Now recognized as a member of the intermediate filament family of proteins, it has become a subject for study in fields as diverse as structural biology, cell biology, gene expression, basic neuroscience, clinical genetics and gene therapy. This review covers each of these areas, presenting an overview of current understanding and controversies regarding GFAP with the goal of stimulating continued study of this fascinating protein.
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spelling pubmed-74407372020-09-02 GFAP at 50 Messing, Albee Brenner, Michael ASN Neuro Article Fifty years have passed since the discovery of glial fibrillary acidic protein (GFAP) by Lawrence Eng and colleagues. Now recognized as a member of the intermediate filament family of proteins, it has become a subject for study in fields as diverse as structural biology, cell biology, gene expression, basic neuroscience, clinical genetics and gene therapy. This review covers each of these areas, presenting an overview of current understanding and controversies regarding GFAP with the goal of stimulating continued study of this fascinating protein. SAGE Publications 2020-08-18 /pmc/articles/PMC7440737/ /pubmed/32811163 http://dx.doi.org/10.1177/1759091420949680 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Article
Messing, Albee
Brenner, Michael
GFAP at 50
title GFAP at 50
title_full GFAP at 50
title_fullStr GFAP at 50
title_full_unstemmed GFAP at 50
title_short GFAP at 50
title_sort gfap at 50
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440737/
https://www.ncbi.nlm.nih.gov/pubmed/32811163
http://dx.doi.org/10.1177/1759091420949680
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