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Protein A-Mediated Binding of Staphylococcus spp. to Antibodies in Flow Cytometric Assays and Reduction of This Binding by Using Fc Receptor Blocking Reagent
Staphylococcus aureus and other coagulase-positive Staphylococcus spp. bind the Fc region of IgG antibodies through expression of protein A (SpA). These species have consequently been a source of false-positive signals in antibody-based assays designed to detect other target bacteria. Here, flow cyt...
Autores principales: | Cronin, Ultan P., Girardeaux, Laura, O’Meara, Elaine, Wilkinson, Martin G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440785/ https://www.ncbi.nlm.nih.gov/pubmed/32591386 http://dx.doi.org/10.1128/AEM.01435-20 |
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