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Squalene-Tetrahymanol Cyclase Expression Enables Sterol-Independent Growth of Saccharomyces cerevisiae

Biosynthesis of sterols, which are considered essential components of virtually all eukaryotic membranes, requires molecular oxygen. Anaerobic growth of the yeast Saccharomyces cerevisiae therefore strictly depends on sterol supplementation of synthetic growth media. Neocallimastigomycota are a grou...

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Detalles Bibliográficos
Autores principales: Wiersma, Sanne J., Mooiman, Christiaan, Giera, Martin, Pronk, Jack T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440791/
https://www.ncbi.nlm.nih.gov/pubmed/32561581
http://dx.doi.org/10.1128/AEM.00672-20