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Transcriptomics uncovers substantial variability associated with alterations in manufacturing processes of macrophage cell therapy products

Gene expression plasticity is central for macrophages’ timely responses to cues from the microenvironment permitting phenotypic adaptation from pro-inflammatory (M1) to wound healing and tissue-regenerative (M2, with several subclasses). Regulatory macrophages are a distinct macrophage type, possess...

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Detalles Bibliográficos
Autores principales: Gurvich, Olga L., Puttonen, Katja A., Bailey, Aubrey, Kailaanmäki, Anssi, Skirdenko, Vita, Sivonen, Minna, Pietikäinen, Sanna, Parker, Nigel R., Ylä-Herttuala, Seppo, Kekarainen, Tuija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441152/
https://www.ncbi.nlm.nih.gov/pubmed/32820219
http://dx.doi.org/10.1038/s41598-020-70967-2

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