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Transcriptomics uncovers substantial variability associated with alterations in manufacturing processes of macrophage cell therapy products
Gene expression plasticity is central for macrophages’ timely responses to cues from the microenvironment permitting phenotypic adaptation from pro-inflammatory (M1) to wound healing and tissue-regenerative (M2, with several subclasses). Regulatory macrophages are a distinct macrophage type, possess...
Autores principales: | Gurvich, Olga L., Puttonen, Katja A., Bailey, Aubrey, Kailaanmäki, Anssi, Skirdenko, Vita, Sivonen, Minna, Pietikäinen, Sanna, Parker, Nigel R., Ylä-Herttuala, Seppo, Kekarainen, Tuija |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441152/ https://www.ncbi.nlm.nih.gov/pubmed/32820219 http://dx.doi.org/10.1038/s41598-020-70967-2 |
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