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An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles

Peptide hormones and neuropeptides encompass a large class of bioactive peptides that regulate physiological processes like anxiety, blood glucose, appetite, inflammation and blood pressure. Here, we execute a focused discovery strategy to provide an extensive map of O-glycans on peptide hormones. W...

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Detalles Bibliográficos
Autores principales: Madsen, Thomas D., Hansen, Lasse H., Hintze, John, Ye, Zilu, Jebari, Shifa, Andersen, Daniel B., Joshi, Hiren J., Ju, Tongzhong, Goetze, Jens P., Martin, Cesar, Rosenkilde, Mette M., Holst, Jens J., Kuhre, Rune E., Goth, Christoffer K., Vakhrushev, Sergey Y., Schjoldager, Katrine T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441158/
https://www.ncbi.nlm.nih.gov/pubmed/32820167
http://dx.doi.org/10.1038/s41467-020-17473-1