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The anesthetic bupivacaine induces cardiotoxicity by targeting L-type voltage-dependent calcium channels

OBJECTIVE: Bupivacaine is an amide local anesthetic with possible side effects that include an irregular heart rate. However, the mechanism of bupivacaine-induced cardiotoxicity has not been fully elucidated, thus we aimed to examine this mechanism. METHODS: We performed electrocardiogram recordings...

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Detalles Bibliográficos
Autores principales: Gao, YaNan, Chen, Bo, Zhang, Xue, Yang, Rui, Hua, QingLi, Li, BaiDong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441289/
https://www.ncbi.nlm.nih.gov/pubmed/32812463
http://dx.doi.org/10.1177/0300060520942619