Suppression of cGMP-Dependent Photoreceptor Cytotoxicity With Mycophenolate Is Neuroprotective in Murine Models of Retinitis Pigmentosa

PURPOSE: To determine the effect of mycophenolate mofetil (MMF) on retinal degeneration on two mouse models of retinitis pigmentosa. METHODS: Intraperitoneal injections of MMF were administered daily in rd10 and c57 mice starting at postoperative day 12 (P12) and rd1 mice starting at P8. The effect...

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Detalles Bibliográficos
Autores principales: Yang, Paul, Lockard, Rachel, Titus, Hope, Hiblar, Jordan, Weller, Kyle, Wafai, Dahlia, Weleber, Richard G., Duvoisin, Robert M., Morgans, Catherine W., Pennesi, Mark E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441375/
https://www.ncbi.nlm.nih.gov/pubmed/32785677
http://dx.doi.org/10.1167/iovs.61.10.25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441375/
https://www.ncbi.nlm.nih.gov/pubmed/32785677
http://dx.doi.org/10.1167/iovs.61.10.25

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