Genetic deletion of microRNA-22 blunts the inflammatory transcriptional response to status epilepticus and exacerbates epilepsy in mice

MicroRNAs perform important roles in the post-transcriptional regulation of gene expression. Sequencing as well as functional studies using antisense oligonucleotides indicate important roles for microRNAs during the development of epilepsy through targeting transcripts involved in neuronal structur...

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Detalles Bibliográficos
Autores principales: Almeida Silva, Luiz F., Reschke, Cristina R., Nguyen, Ngoc T., Langa, Elena, Sanz-Rodriguez, Amaya, Gerbatin, Rogerio R., Temp, Fernanda R., de Freitas, Mayara L., Conroy, Ronan M., Brennan, Gary P., Engel, Tobias, Henshall, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441563/
https://www.ncbi.nlm.nih.gov/pubmed/32825833
http://dx.doi.org/10.1186/s13041-020-00653-x

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