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FACT caught in the act of manipulating the nucleosome
The organization of genomic DNA into nucleosomes profoundly affects all DNA-related processes in eukaryotes. The histone chaperone ‘FAcilitates Chromatin Transcription’ (FACT, consisting of subunits SPT16 and SSRP1(1)) promotes both disassembly and reassembly of nucleosomes during gene transcription...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441595/ https://www.ncbi.nlm.nih.gov/pubmed/31775157 http://dx.doi.org/10.1038/s41586-019-1820-0 |