Increased levels of Stress-inducible phosphoprotein-1 accelerates amyloid-β deposition in a mouse model of Alzheimer’s disease

Molecular chaperones and co-chaperones, which are part of the protein quality control machinery, have been shown to regulate distinct aspects of Alzheimer’s Disease (AD) pathology in multiple ways. Notably, the co-chaperone STI1, which presents increased levels in AD, can protect mammalian neurons f...

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Detalles Bibliográficos
Autores principales: Lackie, Rachel E., Marques-Lopes, Jose, Ostapchenko, Valeriy G., Good, Sarah, Choy, Wing-Yiu, van Oosten-Hawle, Patricija, Pasternak, Stephen H., Prado, Vania F., Prado, Marco A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441634/
https://www.ncbi.nlm.nih.gov/pubmed/32825842
http://dx.doi.org/10.1186/s40478-020-01013-5

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