Myeloid Pannexin-1 mediates acute leukocyte infiltration and leads to worse outcomes after brain trauma

BACKGROUND: Neuroinflammation is a major component of secondary damage after traumatic brain injury (TBI). We recently reported that pharmacological inhibition of Pannexin-1 (Panx1) channels markedly reduced the inflammatory response after TBI. Panx1 channels have been shown to be important conduits...

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Detalles Bibliográficos
Autores principales: Seo, Joon Ho, Dalal, Miloni S., Calderon, Frances, Contreras, Jorge E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441665/
https://www.ncbi.nlm.nih.gov/pubmed/32819386
http://dx.doi.org/10.1186/s12974-020-01917-y

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