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Determination of protein–ligand binding modes using fast multi-dimensional NMR with hyperpolarization
Elucidation of small molecule–protein interactions provides essential information for understanding biological processes such as cellular signaling, as well as for rational drug development. Here, multi-dimensional NMR with sensitivity enhancement by dissolution dynamic nuclear polarization (D-DNP)...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441707/ https://www.ncbi.nlm.nih.gov/pubmed/32874513 http://dx.doi.org/10.1039/d0sc00266f |