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Monitoring Early Changes in Tumor Metabolism in Response to Therapy Using Hyperpolarized (13)C MRSI in a Preclinical Model of Glioma

This study shows the use of hyperpolarized (13)C magnetic resonance spectroscopic imaging (MRSI) to assess therapeutic efficacy in a preclinical tumor model. (13)C-labeled pyruvate was used to monitor early changes in tumor metabolism based on the Warburg effect. High-grade malignant tumors exhibit...

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Detalles Bibliográficos
Autores principales:	Lim, Heeseung, Martínez-Santiesteban, Francisco, Jensen, Michael D., Chen, Albert, Wong, Eugene, Scholl, Timothy J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Grapho Publications, LLC 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442089/ https://www.ncbi.nlm.nih.gov/pubmed/32879899 http://dx.doi.org/10.18383/j.tom.2020.00024

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