Cargando…
Anti-α(4)β(7) monoclonal antibody–conjugated nanoparticles block integrin α(4)β(7) on intravaginal T cells in rhesus macaques
Intravenous administration of anti-α(4)β(7) monoclonal antibody in macaques decreases simian immunodeficiency virus (SIV) vaginal infection and reduces gut SIV loads. Because of potential side effects of systemic administration, a prophylactic strategy based on mucosal administration of anti-α(4)β(7...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442472/ https://www.ncbi.nlm.nih.gov/pubmed/32937372 http://dx.doi.org/10.1126/sciadv.abb9853 |