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The motor cortex uses active suppression to sculpt movement
Even the simplest movements are generated by a remarkably complex pattern of muscle activity. Fast, accurate movements at a single joint are produced by a stereotyped pattern that includes a decrease in any preexisting activity in antagonist muscles. This premovement suppression is necessary to prev...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442473/ https://www.ncbi.nlm.nih.gov/pubmed/32937371 http://dx.doi.org/10.1126/sciadv.abb8395 |
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author | Griffin, Darcy M. Strick, Peter L. |
author_facet | Griffin, Darcy M. Strick, Peter L. |
author_sort | Griffin, Darcy M. |
collection | PubMed |
description | Even the simplest movements are generated by a remarkably complex pattern of muscle activity. Fast, accurate movements at a single joint are produced by a stereotyped pattern that includes a decrease in any preexisting activity in antagonist muscles. This premovement suppression is necessary to prevent the antagonist muscle from opposing movement generated by the agonist muscle. Here, we provide evidence that the primary motor cortex (M1) sends a command signal that generates this premovement suppression. Thus, output neurons in M1 sculpt complex spatiotemporal patterns of motor output not only by actively turning on muscles but also by actively turning them off. |
format | Online Article Text |
id | pubmed-7442473 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | American Association for the Advancement of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-74424732020-09-16 The motor cortex uses active suppression to sculpt movement Griffin, Darcy M. Strick, Peter L. Sci Adv Research Articles Even the simplest movements are generated by a remarkably complex pattern of muscle activity. Fast, accurate movements at a single joint are produced by a stereotyped pattern that includes a decrease in any preexisting activity in antagonist muscles. This premovement suppression is necessary to prevent the antagonist muscle from opposing movement generated by the agonist muscle. Here, we provide evidence that the primary motor cortex (M1) sends a command signal that generates this premovement suppression. Thus, output neurons in M1 sculpt complex spatiotemporal patterns of motor output not only by actively turning on muscles but also by actively turning them off. American Association for the Advancement of Science 2020-08-21 /pmc/articles/PMC7442473/ /pubmed/32937371 http://dx.doi.org/10.1126/sciadv.abb8395 Text en Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC). https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license (https://creativecommons.org/licenses/by-nc/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited. |
spellingShingle | Research Articles Griffin, Darcy M. Strick, Peter L. The motor cortex uses active suppression to sculpt movement |
title | The motor cortex uses active suppression to sculpt movement |
title_full | The motor cortex uses active suppression to sculpt movement |
title_fullStr | The motor cortex uses active suppression to sculpt movement |
title_full_unstemmed | The motor cortex uses active suppression to sculpt movement |
title_short | The motor cortex uses active suppression to sculpt movement |
title_sort | motor cortex uses active suppression to sculpt movement |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442473/ https://www.ncbi.nlm.nih.gov/pubmed/32937371 http://dx.doi.org/10.1126/sciadv.abb8395 |
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