Cargando…

Semaphorin 7A promotes endothelial to mesenchymal transition through ATF3 mediated TGF-β2/Smad signaling

Endothelial to mesenchymal transition (EndMT) is an important pathological change in many diseases. Semaphorin7A (Sema7A) has been reported to regulate nerve and vessel homeostasis, but its role in EndMT remains unclear. Here we investigate the effect of Sema7A on EndMT and the underlying mechanism....

Descripción completa

Detalles Bibliográficos
Autores principales: Hong, Lei, Li, Fengchan, Tang, Chaojun, Li, Ling, Sun, Lili, Li, Xiaoqiang, Zhu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442651/
https://www.ncbi.nlm.nih.gov/pubmed/32826874
http://dx.doi.org/10.1038/s41419-020-02818-x