The D2.mdx mouse as a preclinical model of the skeletal muscle pathology associated with Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is an X-linked, lethal muscle degenerative disease caused by loss of dystrophin protein. DMD has no cure and few treatment options. Preclinical efforts to identify potential DMD therapeutics have been hampered by lack of a small animal model that recapitulates key f...

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Detalles Bibliográficos
Autores principales: Hammers, David W., Hart, Cora C., Matheny, Michael K., Wright, Lillian A., Armellini, Megan, Barton, Elisabeth R., Sweeney, H. Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442653/
https://www.ncbi.nlm.nih.gov/pubmed/32826942
http://dx.doi.org/10.1038/s41598-020-70987-y

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