In vitro analysis reveals necroptotic signaling does not provoke DNA damage or HPRT mutations

Most anticancer drugs provoke apoptotic signaling by damaging DNA or other means. Genotoxic therapies may enhance a patient’s risk of developing “therapy-related cancers” due to the accumulation of oncogenic mutations that may occur in noncancerous cells. Mutations can also form upon apoptotic signa...

Descripción completa

Detalles Bibliográficos
Autores principales: Miles, Mark A., Hawkins, Christine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442655/
https://www.ncbi.nlm.nih.gov/pubmed/32826875
http://dx.doi.org/10.1038/s41419-020-02879-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442655/
https://www.ncbi.nlm.nih.gov/pubmed/32826875
http://dx.doi.org/10.1038/s41419-020-02879-y

Ejemplares similares