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In vitro analysis reveals necroptotic signaling does not provoke DNA damage or HPRT mutations
Most anticancer drugs provoke apoptotic signaling by damaging DNA or other means. Genotoxic therapies may enhance a patient’s risk of developing “therapy-related cancers” due to the accumulation of oncogenic mutations that may occur in noncancerous cells. Mutations can also form upon apoptotic signa...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442655/ https://www.ncbi.nlm.nih.gov/pubmed/32826875 http://dx.doi.org/10.1038/s41419-020-02879-y |