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Long noncoding RNA UCA1 from hypoxia-conditioned hMSC-derived exosomes: a novel molecular target for cardioprotection through miR-873-5p/XIAP axis

Exosomes (Exo) secreted from mesenchymal stem cells (hMSCs) are protective against myocardial injury. The purpose of the study was to investigate the role and mechanisms by which exosomes promote cardiomyocyte survival and function following myocardial infarction (MI). hMSCs were cultured under hypo...

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Detalles Bibliográficos
Autores principales: Sun, Ling, Zhu, Wenwu, Zhao, Pengcheng, Wang, Qingjie, Fan, Baohan, Zhu, Yeqian, Lu, Yao, Chen, Qiushi, Zhang, Jian, Zhang, Fengxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442657/
https://www.ncbi.nlm.nih.gov/pubmed/32826854
http://dx.doi.org/10.1038/s41419-020-02783-5