Cargando…

Single-cell transcriptome profiling reveals neutrophil heterogeneity in homeostasis and infection

The full neutrophil heterogeneity and differentiation landscape remains incompletely characterized. Here we profiled >25,000 differentiating and mature mouse neutrophils using single-cell RNA sequencing to provide a comprehensive transcriptional landscape of neutrophil maturation, function, and f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Xuemei, Shi, Qiang, Wu, Peng, Zhang, Xiaoyu, Kambara, Hiroto, Su, Jiayu, Yu, Hongbo, Park, Shin-Young, Guo, Rongxia, Ren, Qian, Zhang, Sudong, Xu, Yuanfu, Silberstein, Leslie E., Cheng, Tao, Ma, Fengxia, Li, Cheng, Luo, Hongbo R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442692/ https://www.ncbi.nlm.nih.gov/pubmed/32719519 http://dx.doi.org/10.1038/s41590-020-0736-z

Ejemplares similares

Gasdermin D Exerts Anti-inflammatory Effects by Promoting Neutrophil Death
por: Kambara, Hiroto, et al.
Publicado: (2018)

Proteinase 3 Limits the Number of Hematopoietic Stem and Progenitor Cells in Murine Bone Marrow
por: Karatepe, Kutay, et al.
Publicado: (2018)

Bacteria-Induced Acute Inflammation Does Not Reduce the Long-Term Reconstitution Capacity of Bone Marrow Hematopoietic Stem Cells
por: Zhang, Xiaoyu, et al.
Publicado: (2020)

Inflammasome-mediated GSDMD activation facilitates escape of Candida albicans from macrophages
por: Ding, Xionghui, et al.
Publicado: (2021)

Heterogeneity of neutrophils in cancer: one size does not fit all
por: Chen, Song, et al.
Publicado: (2022)

G-CSF maintains controlled neutrophil mobilization during acute inflammation by negatively regulating CXCR2 signaling
por: Bajrami, Besnik, et al.
Publicado: (2016)

Neutrophil-specific depletion of gasdermin D does not protect against murine sepsis
por: Liu, Fei, et al.
Publicado: (2023)

Identification of the Transgene Integration Site and Host Genome Changes in MRP8-Cre/ires-EGFP Transgenic Mice by Targeted Locus Amplification
por: Wang, Guan, et al.
Publicado: (2022)

Single-cell transcriptome profiling reveals heterogeneous neutrophils with prognostic values in sepsis
por: Hong, Yucai, et al.
Publicado: (2022)

Neutrophil Functions in Periodontal Homeostasis
por: Cortés-Vieyra, Ricarda, et al.
Publicado: (2016)

Neutrophils as Components of Mucosal Homeostasis
por: Hall, Caroline H.T., et al.
Publicado: (2017)

Heterogeneity Among Neutrophils
por: Garley, Marzena, et al.
Publicado: (2017)

Heterogeneous Catalysis in Water
por: Lin, Lili, et al.
Publicado: (2021)

Treg Heterogeneity, Function, and Homeostasis
por: Shevyrev, Daniil, et al.
Publicado: (2020)

Neutrophil and T-Cell Homeostasis in the Closed Eye
por: Postnikoff, Cameron K, et al.
Publicado: (2017)

Emerging roles of neutrophils in immune homeostasis
por: Lee, Mingyu, et al.
Publicado: (2022)

Natural Product Celastrol Destabilizes Tubulin Heterodimer and Facilitates Mitotic Cell Death Triggered by Microtubule-Targeting Anti-Cancer Drugs
por: Jo, Hakryul, et al.
Publicado: (2010)

Single Cell Transcriptome Data Analysis Defines the Heterogeneity of Peripheral Nerve Cells in Homeostasis and Regeneration
por: Chen, Bing, et al.
Publicado: (2021)

Enhanced Neutrophil Immune Homeostasis Due to Deletion of PHLPP
por: Ran, Taojing, et al.
Publicado: (2019)

Tumor-Associated Neutrophils and Macrophages—Heterogenous but Not Chaotic
por: Wu, Ling, et al.
Publicado: (2020)

Single-cell transcriptome analysis reveals aberrant stromal cells and heterogeneous endothelial cells in alcohol-induced osteonecrosis of the femoral head
por: Liao, Zheting, et al.
Publicado: (2022)

Ginaton improves neurological function in ischemic stroke rats via inducing autophagy and maintaining mitochondrial homeostasis
por: Li, Xiaoqiang, et al.
Publicado: (2019)

Cellular dynamics in tumour microenvironment along with lung cancer progression underscore spatial and evolutionary heterogeneity of neutrophil
por: Peng, Haoxin, et al.
Publicado: (2023)

Engineered neutrophil-derived exosome-like vesicles for targeted cancer therapy
por: Zhang, Jiahui, et al.
Publicado: (2022)

High-rate and wide-area deposition of epitaxial Si films by mesoplasma chemical vapor deposition
por: Wu, Sudong, et al.
Publicado: (2014)

STAT5 Is an Ambivalent Regulator of Neutrophil Homeostasis
por: Fiévez, Laurence, et al.
Publicado: (2007)

The double‐edged role of neutrophil heterogeneity in inflammatory diseases and cancers
por: Zhou, Wencheng, et al.
Publicado: (2023)

Aerosolization inhalation of non-typeable Haemophilus influenzae outer membrane vesicles contributing to neutrophilic asthma
por: Zhang, Ying, et al.
Publicado: (2023)

Metabolic Control of Treg Cell Stability, Plasticity, and Tissue-Specific Heterogeneity
por: Shi, Hao, et al.
Publicado: (2019)

Functions of CaPhm7 in the regulation of ion homeostasis, drug tolerance, filamentation and virulence in Candida albicans
por: Jiang, Linghuo, et al.
Publicado: (2018)

Current Understanding in Neutrophil Differentiation and Heterogeneity
por: Hong, Chang-Won
Publicado: (2017)

Neutrophils in Tuberculosis: Heterogeneity Shapes the Way?
por: Lyadova, Irina V.
Publicado: (2017)

Identification and characterization of neutrophil heterogeneity in sepsis
por: Qi, Xinxin, et al.
Publicado: (2021)

Editorial: Phenotypic and functional heterogeneity of neutrophils
por: Tamassia, Nicola, et al.
Publicado: (2023)

Single-cell transcriptomic landscape of human blood cells
por: Xie, Xiaowei, et al.
Publicado: (2020)

Methylome and Transcriptome-Based Integration Analysis Identified Molecular Signatures Associated With Meningitis Induced by Glaesserella parasuis
por: Guo, Ling, et al.
Publicado: (2022)

GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever
por: Kanneganti, Apurva, et al.
Publicado: (2018)

Glucose Homeostasis in Relation to Neutrophil Mobilization in Smokers with COPD
por: Pournaras, Nikolaos, et al.
Publicado: (2022)

Heterogeneity of ILC2s in the Intestine; Homeostasis and Pathology
por: Sunaga, Shogo, et al.
Publicado: (2022)

Dissection of transcriptomic and epigenetic heterogeneity of grade 4 gliomas: implications for prognosis
por: Zeng, Chang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_srcpi6ickeeuk1qtlp41bfk2t4