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Molecular basis for DNA repair synthesis on short gaps by mycobacterial Primase-Polymerase C

Cells utilise specialized polymerases from the Primase-Polymerase (Prim-Pol) superfamily to maintain genome stability. Prim-Pol’s function in genome maintenance pathways including replication, repair and damage tolerance. Mycobacteria contain multiple Prim-Pols required for lesion repair, including...

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Detalles Bibliográficos
Autores principales: Brissett, Nigel C., Zabrady, Katerina, Płociński, Przemysław, Bianchi, Julie, Korycka-Machała, Małgorzata, Brzostek, Anna, Dziadek, Jarosław, Doherty, Aidan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442782/
https://www.ncbi.nlm.nih.gov/pubmed/32826907
http://dx.doi.org/10.1038/s41467-020-18012-8