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Development of a Quantitative Immunoassay for Tear Lacritin Proteoforms

PURPOSE: Lacritin is a tear glycoprotein with pro-tearing and pro-ocular surface homeostasis activities that is selectively deficient in most dry eye tears. Proteoforms include an active monomer, inactive polymers, and a splice variant termed lacritin-c. Quantitation of the different proteoforms of...

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Detalles Bibliográficos
Autores principales: Justis, Brooke M., Coburn, Casey E., Tyler, Ethan M., Showalter, Ryan S., Dissler, Brianna J., Li, Melissa, McNamara, Nancy A., Laurie, Gordon W., McKown, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442861/
https://www.ncbi.nlm.nih.gov/pubmed/32879769
http://dx.doi.org/10.1167/tvst.9.9.13