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Hyperspectral Imaging and the Retina: Worth the Wave?
PURPOSE: Hyperspectral imaging is gaining attention in the biomedical field because it generates additional spectral information to study physiological and clinical processes. Several technologies have been described; however an independent, systematic literature overview is lacking, especially in t...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442879/ https://www.ncbi.nlm.nih.gov/pubmed/32879765 http://dx.doi.org/10.1167/tvst.9.9.9 |
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author | Lemmens, Sophie Van Eijgen, Jan Van Keer, Karel Jacob, Julie Moylett, Sinéad De Groef, Lies Vancraenendonck, Toon De Boever, Patrick Stalmans, Ingeborg |
author_facet | Lemmens, Sophie Van Eijgen, Jan Van Keer, Karel Jacob, Julie Moylett, Sinéad De Groef, Lies Vancraenendonck, Toon De Boever, Patrick Stalmans, Ingeborg |
author_sort | Lemmens, Sophie |
collection | PubMed |
description | PURPOSE: Hyperspectral imaging is gaining attention in the biomedical field because it generates additional spectral information to study physiological and clinical processes. Several technologies have been described; however an independent, systematic literature overview is lacking, especially in the field of ophthalmology. This investigation is the first to systematically overview scientific literature specifically regarding retinal hyperspectral imaging. METHODS: A systematic literature review was conducted, in accordance with PRISMA Statement 2009 criteria, in four bibliographic databases: Medline, Embase, Cochrane Database of Systematic Reviews, and Web of Science. RESULTS: Fifty-six articles were found that meet the review criteria. A range of techniques was reported: Fourier analysis, liquid crystal tunable filters, tunable laser sources, dual-slit monochromators, dispersive prisms and gratings, computed tomography, fiber optics, and Fabry-Perrot cavity filter covered complementary metal oxide semiconductor. We present a narrative synthesis and summary tables of findings of the included articles, because methodologic heterogeneity and diverse research topics prevented a meta-analysis being conducted. CONCLUSIONS: Application in ophthalmology is still in its infancy. Most previous experiments have been performed in the field of retinal oximetry, providing valuable information in the diagnosis and monitoring of various ocular diseases. To date, none of these applications have graduated to clinical practice owing to the lack of sufficiently large validation studies. TRANSLATIONAL RELEVANCE: Given the promising results that smaller studies show for hyperspectral imaging (e.g., in Alzheimer's disease), advanced research in larger validation studies is warranted to determine its true clinical potential. |
format | Online Article Text |
id | pubmed-7442879 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Association for Research in Vision and Ophthalmology |
record_format | MEDLINE/PubMed |
spelling | pubmed-74428792020-09-01 Hyperspectral Imaging and the Retina: Worth the Wave? Lemmens, Sophie Van Eijgen, Jan Van Keer, Karel Jacob, Julie Moylett, Sinéad De Groef, Lies Vancraenendonck, Toon De Boever, Patrick Stalmans, Ingeborg Transl Vis Sci Technol Review PURPOSE: Hyperspectral imaging is gaining attention in the biomedical field because it generates additional spectral information to study physiological and clinical processes. Several technologies have been described; however an independent, systematic literature overview is lacking, especially in the field of ophthalmology. This investigation is the first to systematically overview scientific literature specifically regarding retinal hyperspectral imaging. METHODS: A systematic literature review was conducted, in accordance with PRISMA Statement 2009 criteria, in four bibliographic databases: Medline, Embase, Cochrane Database of Systematic Reviews, and Web of Science. RESULTS: Fifty-six articles were found that meet the review criteria. A range of techniques was reported: Fourier analysis, liquid crystal tunable filters, tunable laser sources, dual-slit monochromators, dispersive prisms and gratings, computed tomography, fiber optics, and Fabry-Perrot cavity filter covered complementary metal oxide semiconductor. We present a narrative synthesis and summary tables of findings of the included articles, because methodologic heterogeneity and diverse research topics prevented a meta-analysis being conducted. CONCLUSIONS: Application in ophthalmology is still in its infancy. Most previous experiments have been performed in the field of retinal oximetry, providing valuable information in the diagnosis and monitoring of various ocular diseases. To date, none of these applications have graduated to clinical practice owing to the lack of sufficiently large validation studies. TRANSLATIONAL RELEVANCE: Given the promising results that smaller studies show for hyperspectral imaging (e.g., in Alzheimer's disease), advanced research in larger validation studies is warranted to determine its true clinical potential. The Association for Research in Vision and Ophthalmology 2020-08-05 /pmc/articles/PMC7442879/ /pubmed/32879765 http://dx.doi.org/10.1167/tvst.9.9.9 Text en Copyright 2020 The Authors http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. |
spellingShingle | Review Lemmens, Sophie Van Eijgen, Jan Van Keer, Karel Jacob, Julie Moylett, Sinéad De Groef, Lies Vancraenendonck, Toon De Boever, Patrick Stalmans, Ingeborg Hyperspectral Imaging and the Retina: Worth the Wave? |
title | Hyperspectral Imaging and the Retina: Worth the Wave? |
title_full | Hyperspectral Imaging and the Retina: Worth the Wave? |
title_fullStr | Hyperspectral Imaging and the Retina: Worth the Wave? |
title_full_unstemmed | Hyperspectral Imaging and the Retina: Worth the Wave? |
title_short | Hyperspectral Imaging and the Retina: Worth the Wave? |
title_sort | hyperspectral imaging and the retina: worth the wave? |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442879/ https://www.ncbi.nlm.nih.gov/pubmed/32879765 http://dx.doi.org/10.1167/tvst.9.9.9 |
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