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GRP78 targeting: Hitting two birds with a stone

BACKGROUND: Glucose regulating protein 78 (GRP78) is one member of the Heat Shock Protein family of chaperone proteins (HSPA5) found in eukaryotes. It acts as the master of the Unfolded Protein Response (UPR) process in the lumen of the Endoplasmic Reticulum (ER). SCOPE: Under the stress of unfolded...

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Detalles Bibliográficos
Autores principales: Elfiky, Abdo A., Baghdady, Ahmed M., Ali, Shehab A., Ahmed, Marwan I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442953/
https://www.ncbi.nlm.nih.gov/pubmed/32841659
http://dx.doi.org/10.1016/j.lfs.2020.118317

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