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Two weeks of western diet disrupts liver molecular markers of cholesterol metabolism in rats

BACKGROUND: The present study was designed to test the hypothesis that in the liver, excessive fat accumulation impairs cholesterol metabolism mainly by altering the low-density lipoprotein-receptor (LDL-R) pathway. METHOD: Young male Wistar rats were fed standard (SD), high fat (HFD; 60% kcal) or W...

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Detalles Bibliográficos
Autores principales: St-Amand, Roxane, Ngo Sock, Émilienne T., Quinn, Samantha, Lavoie, Jean-Marc, St-Pierre, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442981/
https://www.ncbi.nlm.nih.gov/pubmed/32825820
http://dx.doi.org/10.1186/s12944-020-01351-2

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