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Cascade-Targeting of Charge-Reversal and Disulfide Bonds Shielding for Efficient DOX Delivery of Multistage Sensitive MSNs-COS-SS-CMC

BACKGROUND: Although pH and redox sensitiveness have been extensively investigated to improve therapeutic efficiency, the effect of disulfide bonds location and pH-triggered charge-reversal on cascade-targeting still need to be further evaluated in cancer treatment with multi-responsive nanoparticle...

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Detalles Bibliográficos
Autores principales: Cui, Lan, Liu, Wentao, Liu, Hao, Qin, Qian, Wu, Shuangxia, He, Suqin, Zhang, Zhenya, Pang, Xinchang, Zhu, Chengshen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443036/
https://www.ncbi.nlm.nih.gov/pubmed/32884269
http://dx.doi.org/10.2147/IJN.S252769