Cargando…

High expression of PTPRM predicts poor prognosis and promotes tumor growth and lymph node metastasis in cervical cancer

The prognosis for cervical cancer (CCa) patients with lymph node metastasis (LNM) is dismal. Elucidation of the molecular mechanisms underlying LNM may provide clinical therapeutic strategies for CCa patients with LNM. However, the precise mechanism of LNM in CCa remains unclear. Herein, we demonstr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Pan, Zhang, Chunyu, Liao, Yuandong, Liu, Junxiu, Huang, Jiaming, Xia, Meng, Chen, Ming, Tan, Hao, He, Weipeng, Xu, Manman, Liu, Tianyu, Ooi, Shiyin, Du, Qiqiao, Qin, Shuhang, Zhu, Yuan, Zou, Qiaojian, Wang, Wei, Yao, Shuzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443137/ https://www.ncbi.nlm.nih.gov/pubmed/32826853 http://dx.doi.org/10.1038/s41419-020-02826-x

Ejemplares similares

Downregulation of LNMAS orchestrates partial EMT and immune escape from macrophage phagocytosis to promote lymph node metastasis of cervical cancer
por: Liao, Yuandong, et al.
Publicado: (2022)

FABP5 promotes lymph node metastasis in cervical cancer by reprogramming fatty acid metabolism
por: Zhang, Chunyu, et al.
Publicado: (2020)

TAB2 Promotes the Stemness and Biological Functions of Cervical Squamous Cell Carcinoma Cells
por: Zhou, Yijia, et al.
Publicado: (2021)

FASN promotes lymph node metastasis in cervical cancer via cholesterol reprogramming and lymphangiogenesis
por: Du, Qiqiao, et al.
Publicado: (2022)

High Expression of Integrin α3 Predicts Poor Prognosis and Promotes Tumor Metastasis and Angiogenesis by Activating the c-Src/Extracellular Signal-Regulated Protein Kinase/Focal Adhesion Kinase Signaling Pathway in Cervical Cancer
por: Du, Qiqiao, et al.
Publicado: (2020)

Circular RNA hsa_circ_0043280 inhibits cervical cancer tumor growth and metastasis via miR-203a-3p/PAQR3 axis
por: Zhang, Chunyu, et al.
Publicado: (2021)

DSG2 expression is correlated with poor prognosis and promotes early-stage cervical cancer
por: Qin, Shuhang, et al.
Publicado: (2020)

Roles of Pyroptosis-Related Gene Signature in Prediction of Endometrial Cancer Outcomes
por: Chen, Yili, et al.
Publicado: (2022)

CircVPRBP inhibits nodal metastasis of cervical cancer by impeding RACK1 O-GlcNAcylation and stability
por: Zhang, Chunyu, et al.
Publicado: (2023)

Patient-derived organoids as personalized avatars and a potential immunotherapy model in cervical cancer
por: Huang, Hua, et al.
Publicado: (2023)

Characterization of long non-coding RNA expression profiles in lymph node metastasis of early-stage cervical cancer
por: SHANG, CHUNLIANG, et al.
Publicado: (2016)

Biological and Clinicopathological Characteristics of OPN in Cervical Cancers
por: Qin, Shuhang, et al.
Publicado: (2022)

PTPRM Is Critical for Synapse Formation Regulated by Zinc Ion
por: Mo, Xiaoqiang, et al.
Publicado: (2022)

Characterization of Poorly Cohesive and Signet Ring Cell Carcinomas and Identification of PTPRM as a Diagnostic Marker
por: Bae, Go Eun, et al.
Publicado: (2022)

HPIP: a predictor of lymph node metastasis and poor survival in cervical cancer
por: Cao, Shan, et al.
Publicado: (2017)

Loss of PTPRM Associates with the Pathogenic Development of Colorectal Adenoma-Carcinoma Sequence
por: Sudhir, Putty-Reddy, et al.
Publicado: (2015)

Effect of flexible patterns of health education on enhancing the compliance of pregnant women from Tibet, China
por: Chen, Jiebing, et al.
Publicado: (2020)

Computed tomography-based radiomic model at node level for the prediction of normal-sized lymph node metastasis in cervical cancer
por: Liu, Yujia, et al.
Publicado: (2021)

PTPRM, a candidate tumor suppressor gene in small intestinal neuroendocrine tumors
por: Barazeghi, Elham, et al.
Publicado: (2019)

Patterns of lymph node metastasis in locally advanced cervical cancer
por: Liu, Zhikai, et al.
Publicado: (2016)

Patterns and clinical significance of cervical lymph node metastasis in papillary thyroid cancer patients with Delphian lymph node metastasis
por: Zheng, Guibin, et al.
Publicado: (2017)

A Cholesterol Homeostasis-Related Gene Signature Predicts Prognosis of Endometrial Cancer and Correlates With Immune Infiltration
por: Chen, Yili, et al.
Publicado: (2021)

Nomogram Predicting Lymph Node Metastasis in the Early-Stage Cervical Cancer
por: Yang, Shimin, et al.
Publicado: (2022)

FABP4 is an independent risk factor for lymph node metastasis and poor prognosis in patients with cervical cancer
por: Li, Guoqing, et al.
Publicado: (2021)

Perineural invasion predicts poor survival and cervical lymph node metastasis in oral squamous cell carcinoma
por: Martínez-Flores, René, et al.
Publicado: (2023)

Lymphoepitheliomas of the cervical lymph nodes.
por: Loke, Y. W.
Publicado: (1965)

PTPRM methylation induced by FN1 promotes the development of glioblastoma by activating STAT3 signalling
por: Song, Jian, et al.
Publicado: (2021)

Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains
por: Hay, Iain M., et al.
Publicado: (2022)

Dermatofibrosarcoma Protuberans of Scalp With Cervical Lymph Node Metastasis
por: Lal, Pawan, et al.
Publicado: (2004)

Cervical lymph node metastasis in renal cell carcinoma
por: Özkiriş, Mahmut, et al.
Publicado: (2011)

DDIAS promotes STAT3 activation by preventing STAT3 recruitment to PTPRM in lung cancer cells
por: Im, Joo-Young, et al.
Publicado: (2020)

Ultrasound of malignant cervical lymph nodes
por: Ahuja, A.T., et al.
Publicado: (2008)

Cervical lymph node diseases in children
por: Lang, Stephan, et al.
Publicado: (2014)

Sentinel lymph node in cervical cancer
por: Akhavan, Setare, et al.
Publicado: (2017)

Patterns and Prognostic Significance of Cervical Lymph Node Metastasis and the Efficacy of Cervical Node Dissection in Esophageal Cancer
por: Kang, Yoonjin, et al.
Publicado: (2017)

Development of a deep learning‐based nomogram for predicting lymph node metastasis in cervical cancer: A multicenter study
por: Liu, Yujia, et al.
Publicado: (2022)

Association between serum lactate dehydrogenase and lymph node metastasis in cervical cancer
por: Huang, Qiuyuan, et al.
Publicado: (2023)

The prognostic miR-532-5p-correlated ceRNA-mediated lipid droplet accumulation drives nodal metastasis of cervical cancer
por: Shang, Chunliang, et al.
Publicado: (2021)

The Pattern of Cervical Lymph Node Metastasis and Risk Factors of Retropharyngeal Lymph Node Metastasis Based on Magnetic Resonance Imaging in Different Sites of Hypopharyngeal Carcinoma
por: Wang, Huili, et al.
Publicado: (2020)

Application of Preoperative Ultrasonography in the Diagnosis of Cervical Lymph Node Metastasis in Thyroid Papillary Carcinoma
por: Zhang, Ailong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_f1lm1ie0ohmbg0prqu0h6hcjrl