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Caring for cancer patients in the Covid pandemic: choosing between the devil and deep sea

BACKGROUND: Healthcare is an essential service at any time more so in the crisis like Covid. With increase in number of cases and mortality from Covid, the primary focus is shifted to the management of the Covid crisis and other health emergencies thus affecting normal health services and routine tr...

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Autores principales: Chakraborty, Mainak, Pandey, Manoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443152/
https://www.ncbi.nlm.nih.gov/pubmed/32828120
http://dx.doi.org/10.1186/s12957-020-02002-7
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author Chakraborty, Mainak
Pandey, Manoj
author_facet Chakraborty, Mainak
Pandey, Manoj
author_sort Chakraborty, Mainak
collection PubMed
description BACKGROUND: Healthcare is an essential service at any time more so in the crisis like Covid. With increase in number of cases and mortality from Covid, the primary focus is shifted to the management of the Covid crisis and other health emergencies thus affecting normal health services and routine treatment of other diseases like cancer. METHODS: This article reviews the published literature and guidelines on Covid and cancer and discusses them to optimize the care of cancer patients during Covid pandemic to improve treatment outcomes. RESULTS: The results of the review of published literature show a twofold increase in probability of getting CoV2 infection by the cancer patients and a four-fold increase in chance of death. On the other hand, if left untreated a 20% increase in cancer death is expected. Data further show that none of the medicines like remdesivir, hydroxy chloroquin, dexamethasone, or azithromycin improves survival and response to Covid in cancer patients. Surgical results too show similar outcome before and after the pandemic though most of these report on highly selected patients populations. CONCLUSIONS: The Covid 2019 pandemic places cancer patients in a very difficult situation wherein if they seek treatment, they are exposing themselves to a risk of developing CoV2 infection and if they do not, the probability of dying without treatment increases. Hence, for them it is a choice between the devil and deep sea, and it is for the healthcare providers to triage patients and treat who cannot wait even though the data from the carefully selected cohort of patients show no increase in mortality or morbidity from treatment during Covid.
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spelling pubmed-74431522020-08-24 Caring for cancer patients in the Covid pandemic: choosing between the devil and deep sea Chakraborty, Mainak Pandey, Manoj World J Surg Oncol Review BACKGROUND: Healthcare is an essential service at any time more so in the crisis like Covid. With increase in number of cases and mortality from Covid, the primary focus is shifted to the management of the Covid crisis and other health emergencies thus affecting normal health services and routine treatment of other diseases like cancer. METHODS: This article reviews the published literature and guidelines on Covid and cancer and discusses them to optimize the care of cancer patients during Covid pandemic to improve treatment outcomes. RESULTS: The results of the review of published literature show a twofold increase in probability of getting CoV2 infection by the cancer patients and a four-fold increase in chance of death. On the other hand, if left untreated a 20% increase in cancer death is expected. Data further show that none of the medicines like remdesivir, hydroxy chloroquin, dexamethasone, or azithromycin improves survival and response to Covid in cancer patients. Surgical results too show similar outcome before and after the pandemic though most of these report on highly selected patients populations. CONCLUSIONS: The Covid 2019 pandemic places cancer patients in a very difficult situation wherein if they seek treatment, they are exposing themselves to a risk of developing CoV2 infection and if they do not, the probability of dying without treatment increases. Hence, for them it is a choice between the devil and deep sea, and it is for the healthcare providers to triage patients and treat who cannot wait even though the data from the carefully selected cohort of patients show no increase in mortality or morbidity from treatment during Covid. BioMed Central 2020-08-22 /pmc/articles/PMC7443152/ /pubmed/32828120 http://dx.doi.org/10.1186/s12957-020-02002-7 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Chakraborty, Mainak
Pandey, Manoj
Caring for cancer patients in the Covid pandemic: choosing between the devil and deep sea
title Caring for cancer patients in the Covid pandemic: choosing between the devil and deep sea
title_full Caring for cancer patients in the Covid pandemic: choosing between the devil and deep sea
title_fullStr Caring for cancer patients in the Covid pandemic: choosing between the devil and deep sea
title_full_unstemmed Caring for cancer patients in the Covid pandemic: choosing between the devil and deep sea
title_short Caring for cancer patients in the Covid pandemic: choosing between the devil and deep sea
title_sort caring for cancer patients in the covid pandemic: choosing between the devil and deep sea
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443152/
https://www.ncbi.nlm.nih.gov/pubmed/32828120
http://dx.doi.org/10.1186/s12957-020-02002-7
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