Cargando…
ELABELA attenuates deoxycorticosterone acetate/salt-induced hypertension and renal injury by inhibition of NADPH oxidase/ROS/NLRP3 inflammasome pathway
ELABELA (ELA), a 32-residue hormone peptide abundantly expressed in adult kidneys, has been identified as a novel endogenous ligand for APJ/Apelin receptor. The aim of this study was to investigate the role of ELA in deoxycorticosterone acetate (DOCA)/salt-induced hypertension and further explore th...
Autores principales: | Chen, Zhida, Wu, Chunying, Liu, Yuting, Li, Haonan, Zhu, Yeyan, Huang, Cailing, Lin, Huangbo, Qiao, Qiao, Huang, Mengming, Zhu, Qing, Wang, Lei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443189/ https://www.ncbi.nlm.nih.gov/pubmed/32829380 http://dx.doi.org/10.1038/s41419-020-02912-0 |
Ejemplares similares
-
ELABELA/APJ Axis Prevents Diabetic Glomerular Endothelial Injury by Regulating AMPK/NLRP3 Pathway
por: Chen, Zhida, et al.
Publicado: (2023) -
NADPH Oxidase 2 Regulates NLRP3 Inflammasome Activation in the Brain after Traumatic Brain Injury
por: Ma, Merry W., et al.
Publicado: (2017) -
Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function
por: Sokolovska, Anna, et al.
Publicado: (2013) -
Long-Term Inhibition of Xanthine Oxidase by Febuxostat Does Not Decrease Blood Pressure in Deoxycorticosterone Acetate (DOCA)-Salt Hypertensive Rats
por: Szasz, Theodora, et al.
Publicado: (2013) -
RAGE-aptamer attenuates deoxycorticosterone acetate/salt-induced renal injury in mice
por: Taguchi, Kensei, et al.
Publicado: (2018)