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The Development and Application of a Base Editor in Biomedicine

Using a base editor to generate monogenic disease models and correct pathogenic point mutations is a breakthrough technology for exploration and treatment of human diseases. As a burgeoning approach for genomic modification, the fused CRISPR/Cas9 with various deaminase separately has significantly i...

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Detalles Bibliográficos
Autores principales: Wang, Fang, Zeng, Yuqiang, Wang, Yi, Niu, Yuyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443245/
https://www.ncbi.nlm.nih.gov/pubmed/32855962
http://dx.doi.org/10.1155/2020/2907623