Carnosic acid increases sorafenib-induced inhibition of ERK1/2 and STAT3 signaling which contributes to reduced cell proliferation and survival of hepatocellular carcinoma cells

Hepatocellular carcinoma (HCC) has increasing worldwide incidence but when unresectable lacks curative options. Treatment with a kinase inhibitor Sorafenib (Sf), while initially effective, results in only short increases in patient survival, thus there is a need for improved treatment regimens. Nume...

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Detalles Bibliográficos
Autores principales: Wang, Xuening, Gupta, Priya, Jramne, Yasmeen, Danilenko, Michael, Liu, Dongfang, Studzinski, George P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443370/
https://www.ncbi.nlm.nih.gov/pubmed/32913557
http://dx.doi.org/10.18632/oncotarget.27687

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