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Investigation of the genetic variation in ACE2 on the structural recognition by the novel coronavirus (SARS-CoV-2)

BACKGROUND: The outbreak of coronavirus disease (COVID-19) was caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), through its surface spike glycoprotein (S-protein) recognition on the receptor Angiotensin-converting enzyme 2 (ACE2) in humans. However, it remains unclear how gene...

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Detalles Bibliográficos
Autores principales: Guo, Xingyi, Chen, Zhishan, Xia, Yumin, Lin, Weiqiang, Li, Hongzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443814/
https://www.ncbi.nlm.nih.gov/pubmed/32831104
http://dx.doi.org/10.1186/s12967-020-02486-7