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Gastric neuroendocrine tumor: A practical literature review
Gastric neuroendocrine tumors are gastric neoplasms originating from enterochromaffin type cells and are inserted in a larger group, named gastroenteropancreatic neuroendocrine tumors. They are considered rare and variable in terms of their clinical, morphological and functional characteristics and...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443841/ https://www.ncbi.nlm.nih.gov/pubmed/32879663 http://dx.doi.org/10.4251/wjgo.v12.i8.850 |
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author | Roberto, Gabriel Antonio Rodrigues, Carolina Magalhães Britto Peixoto, Renata D’Alpino Younes, Riad Naim |
author_facet | Roberto, Gabriel Antonio Rodrigues, Carolina Magalhães Britto Peixoto, Renata D’Alpino Younes, Riad Naim |
author_sort | Roberto, Gabriel Antonio |
collection | PubMed |
description | Gastric neuroendocrine tumors are gastric neoplasms originating from enterochromaffin type cells and are inserted in a larger group, named gastroenteropancreatic neuroendocrine tumors. They are considered rare and variable in terms of their clinical, morphological and functional characteristics and may be indolent or aggressive. They are classified into types I, II and III, according to their pathophysiology, behavior and treatment. Their diagnosis occurs, in most cases, incidentally during upper digestive endoscopies, presenting as simple gastric polyps. Most cases (type I and type II) are related to hypergastrinemia, can be multiple and are treated by endoscopic resection, whenever possible. The use of somatostatin analogs for tumor control may be one of the options for therapy, in addition to total or subtotal gastrectomy for selected cases. Adjuvant chemotherapy is only reserved for poorly differentiated neuroendocrine carcinomas. Although rare, gastric neuroendocrine tumors have an increasing incidence over the years, therefore deserving more comprehensive studies on its adequate treatment. The present study reviews and updates management recommendations for gastric neuroendocrine tumors. |
format | Online Article Text |
id | pubmed-7443841 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-74438412020-09-01 Gastric neuroendocrine tumor: A practical literature review Roberto, Gabriel Antonio Rodrigues, Carolina Magalhães Britto Peixoto, Renata D’Alpino Younes, Riad Naim World J Gastrointest Oncol Minireviews Gastric neuroendocrine tumors are gastric neoplasms originating from enterochromaffin type cells and are inserted in a larger group, named gastroenteropancreatic neuroendocrine tumors. They are considered rare and variable in terms of their clinical, morphological and functional characteristics and may be indolent or aggressive. They are classified into types I, II and III, according to their pathophysiology, behavior and treatment. Their diagnosis occurs, in most cases, incidentally during upper digestive endoscopies, presenting as simple gastric polyps. Most cases (type I and type II) are related to hypergastrinemia, can be multiple and are treated by endoscopic resection, whenever possible. The use of somatostatin analogs for tumor control may be one of the options for therapy, in addition to total or subtotal gastrectomy for selected cases. Adjuvant chemotherapy is only reserved for poorly differentiated neuroendocrine carcinomas. Although rare, gastric neuroendocrine tumors have an increasing incidence over the years, therefore deserving more comprehensive studies on its adequate treatment. The present study reviews and updates management recommendations for gastric neuroendocrine tumors. Baishideng Publishing Group Inc 2020-08-15 2020-08-15 /pmc/articles/PMC7443841/ /pubmed/32879663 http://dx.doi.org/10.4251/wjgo.v12.i8.850 Text en ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Minireviews Roberto, Gabriel Antonio Rodrigues, Carolina Magalhães Britto Peixoto, Renata D’Alpino Younes, Riad Naim Gastric neuroendocrine tumor: A practical literature review |
title | Gastric neuroendocrine tumor: A practical literature review |
title_full | Gastric neuroendocrine tumor: A practical literature review |
title_fullStr | Gastric neuroendocrine tumor: A practical literature review |
title_full_unstemmed | Gastric neuroendocrine tumor: A practical literature review |
title_short | Gastric neuroendocrine tumor: A practical literature review |
title_sort | gastric neuroendocrine tumor: a practical literature review |
topic | Minireviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443841/ https://www.ncbi.nlm.nih.gov/pubmed/32879663 http://dx.doi.org/10.4251/wjgo.v12.i8.850 |
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