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Gastric neuroendocrine tumor: A practical literature review

Gastric neuroendocrine tumors are gastric neoplasms originating from enterochromaffin type cells and are inserted in a larger group, named gastroenteropancreatic neuroendocrine tumors. They are considered rare and variable in terms of their clinical, morphological and functional characteristics and...

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Autores principales: Roberto, Gabriel Antonio, Rodrigues, Carolina Magalhães Britto, Peixoto, Renata D’Alpino, Younes, Riad Naim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443841/
https://www.ncbi.nlm.nih.gov/pubmed/32879663
http://dx.doi.org/10.4251/wjgo.v12.i8.850
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author Roberto, Gabriel Antonio
Rodrigues, Carolina Magalhães Britto
Peixoto, Renata D’Alpino
Younes, Riad Naim
author_facet Roberto, Gabriel Antonio
Rodrigues, Carolina Magalhães Britto
Peixoto, Renata D’Alpino
Younes, Riad Naim
author_sort Roberto, Gabriel Antonio
collection PubMed
description Gastric neuroendocrine tumors are gastric neoplasms originating from enterochromaffin type cells and are inserted in a larger group, named gastroenteropancreatic neuroendocrine tumors. They are considered rare and variable in terms of their clinical, morphological and functional characteristics and may be indolent or aggressive. They are classified into types I, II and III, according to their pathophysiology, behavior and treatment. Their diagnosis occurs, in most cases, incidentally during upper digestive endoscopies, presenting as simple gastric polyps. Most cases (type I and type II) are related to hypergastrinemia, can be multiple and are treated by endoscopic resection, whenever possible. The use of somatostatin analogs for tumor control may be one of the options for therapy, in addition to total or subtotal gastrectomy for selected cases. Adjuvant chemotherapy is only reserved for poorly differentiated neuroendocrine carcinomas. Although rare, gastric neuroendocrine tumors have an increasing incidence over the years, therefore deserving more comprehensive studies on its adequate treatment. The present study reviews and updates management recommendations for gastric neuroendocrine tumors.
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spelling pubmed-74438412020-09-01 Gastric neuroendocrine tumor: A practical literature review Roberto, Gabriel Antonio Rodrigues, Carolina Magalhães Britto Peixoto, Renata D’Alpino Younes, Riad Naim World J Gastrointest Oncol Minireviews Gastric neuroendocrine tumors are gastric neoplasms originating from enterochromaffin type cells and are inserted in a larger group, named gastroenteropancreatic neuroendocrine tumors. They are considered rare and variable in terms of their clinical, morphological and functional characteristics and may be indolent or aggressive. They are classified into types I, II and III, according to their pathophysiology, behavior and treatment. Their diagnosis occurs, in most cases, incidentally during upper digestive endoscopies, presenting as simple gastric polyps. Most cases (type I and type II) are related to hypergastrinemia, can be multiple and are treated by endoscopic resection, whenever possible. The use of somatostatin analogs for tumor control may be one of the options for therapy, in addition to total or subtotal gastrectomy for selected cases. Adjuvant chemotherapy is only reserved for poorly differentiated neuroendocrine carcinomas. Although rare, gastric neuroendocrine tumors have an increasing incidence over the years, therefore deserving more comprehensive studies on its adequate treatment. The present study reviews and updates management recommendations for gastric neuroendocrine tumors. Baishideng Publishing Group Inc 2020-08-15 2020-08-15 /pmc/articles/PMC7443841/ /pubmed/32879663 http://dx.doi.org/10.4251/wjgo.v12.i8.850 Text en ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Minireviews
Roberto, Gabriel Antonio
Rodrigues, Carolina Magalhães Britto
Peixoto, Renata D’Alpino
Younes, Riad Naim
Gastric neuroendocrine tumor: A practical literature review
title Gastric neuroendocrine tumor: A practical literature review
title_full Gastric neuroendocrine tumor: A practical literature review
title_fullStr Gastric neuroendocrine tumor: A practical literature review
title_full_unstemmed Gastric neuroendocrine tumor: A practical literature review
title_short Gastric neuroendocrine tumor: A practical literature review
title_sort gastric neuroendocrine tumor: a practical literature review
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443841/
https://www.ncbi.nlm.nih.gov/pubmed/32879663
http://dx.doi.org/10.4251/wjgo.v12.i8.850
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