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Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovary

We sequenced more than 52,500 single cells from embryonic day 11.5 (E11.5) postembryonic day 5 (P5) gonads and performed lineage tracing to analyze primordial follicles and wave 1 medullar follicles during mouse fetal and perinatal oogenesis. Germ cells clustered into six meiotic substages, as well...

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Detalles Bibliográficos
Autores principales: Niu, Wanbao, Spradling, Allan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443898/
https://www.ncbi.nlm.nih.gov/pubmed/32759216
http://dx.doi.org/10.1073/pnas.2005570117