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Epithelioid malignant peripheral nerve sheath tumor arising in schwannoma

Epithelioid malignant peripheral nerve sheath tumor (EMPNST, malignant epithelioid schwannoma) is a rare variant of malignant peripheral nerve sheath tumor that has morphologic and immunophenotypic overlap with a variety of epithelioid neoplasms. Because of its rarity it may be potentially underreco...

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Detalles Bibliográficos
Autores principales: Heatley, Nicholas, Kolson Kokohaare, Eva, Strauss, Dirk C, Hallin, Magnus, Jones, Robin L, Fisher, Cyril, Thway, Khin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443986/
https://www.ncbi.nlm.nih.gov/pubmed/32913618
http://dx.doi.org/10.1177/2036361320950862
Descripción
Sumario:Epithelioid malignant peripheral nerve sheath tumor (EMPNST, malignant epithelioid schwannoma) is a rare variant of malignant peripheral nerve sheath tumor that has morphologic and immunophenotypic overlap with a variety of epithelioid neoplasms. Because of its rarity it may be potentially underrecognized. We describe a case arising in the subcutis of the thigh in a 25 year-old female, and discuss the pathologic features and differential diagnosis.