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Inhibition of oxidative stress and NLRP3 inflammasome by Saikosaponin-d alleviates acute liver injury in carbon tetrachloride-induced hepatitis in mice
NLRP3 inflammasome activation results in severe liver inflammation and injury. Saikosaponin-d (SSd) possesses anti-inflammatory and hepatoprotective effects. This study aimed to determine the protective effects of SSd on carbon tetrachloride (CCl(4))-induced acute liver injury in mice, and whether o...
Autores principales: | Chen, Yirong, Que, Renye, Lin, Liubing, Shen, Yanting, Liu, Jinkai, Li, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444099/ https://www.ncbi.nlm.nih.gov/pubmed/32816567 http://dx.doi.org/10.1177/2058738420950593 |
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