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Inhibition of oxidative stress and NLRP3 inflammasome by Saikosaponin-d alleviates acute liver injury in carbon tetrachloride-induced hepatitis in mice

NLRP3 inflammasome activation results in severe liver inflammation and injury. Saikosaponin-d (SSd) possesses anti-inflammatory and hepatoprotective effects. This study aimed to determine the protective effects of SSd on carbon tetrachloride (CCl(4))-induced acute liver injury in mice, and whether o...

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Detalles Bibliográficos
Autores principales: Chen, Yirong, Que, Renye, Lin, Liubing, Shen, Yanting, Liu, Jinkai, Li, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444099/
https://www.ncbi.nlm.nih.gov/pubmed/32816567
http://dx.doi.org/10.1177/2058738420950593

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