Transplanted Human Neural Progenitor Cells Attenuate Motor Dysfunction and Lengthen Longevity in a Rat Model of Ataxia

The spastic Han Wistar (sHW) rat serves as a model for human ataxia presenting symptoms of motor deterioration, weight loss, shortened lifespan, and Purkinje neuron loss. Past studies revealed that human neural progenitor cells (NPCs) improved ataxic symptoms at 20 d posttransplantation in sHW rats....

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Detalles Bibliográficos
Autores principales: Tierney, Wesley M., Uhlendorf, Toni L., Lemus, Aaron J.J., Ortega, Bianca A., Magaña, Jesse, Ochoa, Jessica, Van Trigt, William, Cruz, Angelica, Kopyov, Alex, Kopyov, Oleg V., Cohen, Randy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444227/
https://www.ncbi.nlm.nih.gov/pubmed/32314612
http://dx.doi.org/10.1177/0963689720920275

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