Ceramide induces MMP-9 expression through JAK2/STAT3 pathway in airway epithelium

BACKGROUND: Ceramide, a bioactive lipid, plays an essential role in the development of several pulmonary inflammatory diseases. Matrix metallopeptidase 9 (MMP-9) regulates the synthesis and degradation of extracellular matrix, and is associated with airway remodeling and tissue injury. This study wa...

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Detalles Bibliográficos
Autores principales: Xuan, Lingling, Han, Feifei, Gong, Lili, Lv, Yali, Wan, Zirui, Liu, He, Ren, Lulu, Yang, Song, Zhang, Wen, Li, Ting, Tan, Chunting, Liu, Lihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444274/
https://www.ncbi.nlm.nih.gov/pubmed/32829707
http://dx.doi.org/10.1186/s12944-020-01373-w

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