Modeling COVID-19 with Human Pluripotent Stem Cell-Derived Cells Reveals Synergistic Effects of Anti-inflammatory Macrophages with ACE2 Inhibition Against SARS-CoV-2

Dysfunctional immune responses contribute critically to the progression of Coronavirus Disease-2019 (COVID-19) from mild to severe stages including fatality, with pro-inflammatory macrophages as one of the main mediators of lung hyper-inflammation. Therefore, there is an urgent need to better unders...

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Detalles Bibliográficos
Autores principales: Duan, Fuyu, Guo, Liyan, Yang, Liuliu, Han, Yuling, Thakur, Abhimanyu, Nilsson-Payant, Benjamin E., Wang, Pengfei, Zhang, Zhao, Yan Ma, Chui, Zhou, Xiaoya, Han, Teng, Zhang, Tuo, Wang, Xing, Xu, Dong, Duan, Xiaohua, Xiang, Jenny, Tse, Hung-fat, Liao, Can, Luo, Weiren, Huang, Fang-Ping, Chen, Ya-Wen, Evans, Todd, Schwartz, Robert E., tenOever, Benjamin, Ho, David D., Chen, Shuibing, Na, Jie, Lian, Qizhou, Chen, Huanhuan Joyce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444287/
https://www.ncbi.nlm.nih.gov/pubmed/32839764
http://dx.doi.org/10.21203/rs.3.rs-62758/v2

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