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Significance of high resolution MRI in the identification of carotid plaque

The stability of carotid artery plaque serves a key role in the occurrence of stroke. The present study was based on the recruitment of patients with acute ischemic cerebrovascular disease. High-resolution magnetic resonance imaging (HR-MRI) was used to identify the nature of carotid artery plaque,...

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Autores principales: Sun, Yong, Xu, Lei, Jiang, Yan, Ma, Ming, Wang, Xin-Yi, Xing, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444342/
https://www.ncbi.nlm.nih.gov/pubmed/32855717
http://dx.doi.org/10.3892/etm.2020.9091
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author Sun, Yong
Xu, Lei
Jiang, Yan
Ma, Ming
Wang, Xin-Yi
Xing, Ying
author_facet Sun, Yong
Xu, Lei
Jiang, Yan
Ma, Ming
Wang, Xin-Yi
Xing, Ying
author_sort Sun, Yong
collection PubMed
description The stability of carotid artery plaque serves a key role in the occurrence of stroke. The present study was based on the recruitment of patients with acute ischemic cerebrovascular disease. High-resolution magnetic resonance imaging (HR-MRI) was used to identify the nature of carotid artery plaque, and the results were then used to manage the high-risk group of stroke. The patients were divided equally into a symptomatic group (36 cases) and an asymptomatic group (36 cases). According to the degree of carotid artery stenosis, the patients were divided into mild, moderate and severe stenosis groups, each group comprising 12 patients, and HR-MRI was performed. The proportion of patients with vulnerable plaque in the symptomatic group was higher compared with that in the asymptomatic group (P<0.05). The more severe the stenosis, the higher the proportion of vulnerable plaque that was identified (P<0.05). Compared with carotid ultrasound, HR-MRI was indicated to have the capability to both identify and quantify the different components in the plaque, allowing an assessment of its properties. In conclusion, the present study demonstrated that carotid HR-MRI is able to distinguish and quantify the different components of plaque, which may prove to be helpful for the hierarchical management of a population at high risk of stroke.
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spelling pubmed-74443422020-08-26 Significance of high resolution MRI in the identification of carotid plaque Sun, Yong Xu, Lei Jiang, Yan Ma, Ming Wang, Xin-Yi Xing, Ying Exp Ther Med Articles The stability of carotid artery plaque serves a key role in the occurrence of stroke. The present study was based on the recruitment of patients with acute ischemic cerebrovascular disease. High-resolution magnetic resonance imaging (HR-MRI) was used to identify the nature of carotid artery plaque, and the results were then used to manage the high-risk group of stroke. The patients were divided equally into a symptomatic group (36 cases) and an asymptomatic group (36 cases). According to the degree of carotid artery stenosis, the patients were divided into mild, moderate and severe stenosis groups, each group comprising 12 patients, and HR-MRI was performed. The proportion of patients with vulnerable plaque in the symptomatic group was higher compared with that in the asymptomatic group (P<0.05). The more severe the stenosis, the higher the proportion of vulnerable plaque that was identified (P<0.05). Compared with carotid ultrasound, HR-MRI was indicated to have the capability to both identify and quantify the different components in the plaque, allowing an assessment of its properties. In conclusion, the present study demonstrated that carotid HR-MRI is able to distinguish and quantify the different components of plaque, which may prove to be helpful for the hierarchical management of a population at high risk of stroke. D.A. Spandidos 2020-10 2020-08-03 /pmc/articles/PMC7444342/ /pubmed/32855717 http://dx.doi.org/10.3892/etm.2020.9091 Text en Copyright: © Sun et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
Sun, Yong
Xu, Lei
Jiang, Yan
Ma, Ming
Wang, Xin-Yi
Xing, Ying
Significance of high resolution MRI in the identification of carotid plaque
title Significance of high resolution MRI in the identification of carotid plaque
title_full Significance of high resolution MRI in the identification of carotid plaque
title_fullStr Significance of high resolution MRI in the identification of carotid plaque
title_full_unstemmed Significance of high resolution MRI in the identification of carotid plaque
title_short Significance of high resolution MRI in the identification of carotid plaque
title_sort significance of high resolution mri in the identification of carotid plaque
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444342/
https://www.ncbi.nlm.nih.gov/pubmed/32855717
http://dx.doi.org/10.3892/etm.2020.9091
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