Cargando…
Estimating the Effect of Depression on HIV Transmission Risk Behaviors Among People Who Inject Drugs in Vietnam: A Causal Approach
The burden of depression and HIV is high among people who inject drugs (PWID), yet the effect of depression on transmission risk behaviors is not well understood in this population. Using causal inference methods, we analyzed data from 455 PWID living with HIV in Vietnam 2009–2013. Study visits ever...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444452/ https://www.ncbi.nlm.nih.gov/pubmed/32833193 http://dx.doi.org/10.1007/s10461-020-03007-9 |
_version_ | 1783573809264066560 |
---|---|
author | Levintow, Sara N. Pence, Brian W. Powers, Kimberly A. Sripaipan, Teerada Ha, Tran Viet Chu, Viet Anh Quan, Vu Minh Latkin, Carl A. Go, Vivian F. |
author_facet | Levintow, Sara N. Pence, Brian W. Powers, Kimberly A. Sripaipan, Teerada Ha, Tran Viet Chu, Viet Anh Quan, Vu Minh Latkin, Carl A. Go, Vivian F. |
author_sort | Levintow, Sara N. |
collection | PubMed |
description | The burden of depression and HIV is high among people who inject drugs (PWID), yet the effect of depression on transmission risk behaviors is not well understood in this population. Using causal inference methods, we analyzed data from 455 PWID living with HIV in Vietnam 2009–2013. Study visits every 6 months over 2 years measured depressive symptoms in the past week and injecting and sexual behaviors in the prior 3 months. Severe depressive symptoms (vs. mild/no symptoms) increased injection equipment sharing (risk difference [RD] = 3.9 percentage points, 95% CI −1.7, 9.6) but not condomless sex (RD = −1.8, 95% CI −6.4, 2.8) as reported 6 months later. The cross-sectional association with injection equipment sharing at the same visit (RD = 6.2, 95% CI 1.4, 11.0) was stronger than the longitudinal effect. Interventions on depression among PWID may decrease sharing of injection equipment and the corresponding risk of HIV transmission. Clinical trial registration ClinicalTrials.gov NCT01689545. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10461-020-03007-9) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-7444452 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-74444522020-08-26 Estimating the Effect of Depression on HIV Transmission Risk Behaviors Among People Who Inject Drugs in Vietnam: A Causal Approach Levintow, Sara N. Pence, Brian W. Powers, Kimberly A. Sripaipan, Teerada Ha, Tran Viet Chu, Viet Anh Quan, Vu Minh Latkin, Carl A. Go, Vivian F. AIDS Behav Original Paper The burden of depression and HIV is high among people who inject drugs (PWID), yet the effect of depression on transmission risk behaviors is not well understood in this population. Using causal inference methods, we analyzed data from 455 PWID living with HIV in Vietnam 2009–2013. Study visits every 6 months over 2 years measured depressive symptoms in the past week and injecting and sexual behaviors in the prior 3 months. Severe depressive symptoms (vs. mild/no symptoms) increased injection equipment sharing (risk difference [RD] = 3.9 percentage points, 95% CI −1.7, 9.6) but not condomless sex (RD = −1.8, 95% CI −6.4, 2.8) as reported 6 months later. The cross-sectional association with injection equipment sharing at the same visit (RD = 6.2, 95% CI 1.4, 11.0) was stronger than the longitudinal effect. Interventions on depression among PWID may decrease sharing of injection equipment and the corresponding risk of HIV transmission. Clinical trial registration ClinicalTrials.gov NCT01689545. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10461-020-03007-9) contains supplementary material, which is available to authorized users. Springer US 2020-08-24 2021 /pmc/articles/PMC7444452/ /pubmed/32833193 http://dx.doi.org/10.1007/s10461-020-03007-9 Text en © Springer Science+Business Media, LLC, part of Springer Nature 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Original Paper Levintow, Sara N. Pence, Brian W. Powers, Kimberly A. Sripaipan, Teerada Ha, Tran Viet Chu, Viet Anh Quan, Vu Minh Latkin, Carl A. Go, Vivian F. Estimating the Effect of Depression on HIV Transmission Risk Behaviors Among People Who Inject Drugs in Vietnam: A Causal Approach |
title | Estimating the Effect of Depression on HIV Transmission Risk Behaviors Among People Who Inject Drugs in Vietnam: A Causal Approach |
title_full | Estimating the Effect of Depression on HIV Transmission Risk Behaviors Among People Who Inject Drugs in Vietnam: A Causal Approach |
title_fullStr | Estimating the Effect of Depression on HIV Transmission Risk Behaviors Among People Who Inject Drugs in Vietnam: A Causal Approach |
title_full_unstemmed | Estimating the Effect of Depression on HIV Transmission Risk Behaviors Among People Who Inject Drugs in Vietnam: A Causal Approach |
title_short | Estimating the Effect of Depression on HIV Transmission Risk Behaviors Among People Who Inject Drugs in Vietnam: A Causal Approach |
title_sort | estimating the effect of depression on hiv transmission risk behaviors among people who inject drugs in vietnam: a causal approach |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444452/ https://www.ncbi.nlm.nih.gov/pubmed/32833193 http://dx.doi.org/10.1007/s10461-020-03007-9 |
work_keys_str_mv | AT levintowsaran estimatingtheeffectofdepressiononhivtransmissionriskbehaviorsamongpeoplewhoinjectdrugsinvietnamacausalapproach AT pencebrianw estimatingtheeffectofdepressiononhivtransmissionriskbehaviorsamongpeoplewhoinjectdrugsinvietnamacausalapproach AT powerskimberlya estimatingtheeffectofdepressiononhivtransmissionriskbehaviorsamongpeoplewhoinjectdrugsinvietnamacausalapproach AT sripaipanteerada estimatingtheeffectofdepressiononhivtransmissionriskbehaviorsamongpeoplewhoinjectdrugsinvietnamacausalapproach AT hatranviet estimatingtheeffectofdepressiononhivtransmissionriskbehaviorsamongpeoplewhoinjectdrugsinvietnamacausalapproach AT chuvietanh estimatingtheeffectofdepressiononhivtransmissionriskbehaviorsamongpeoplewhoinjectdrugsinvietnamacausalapproach AT quanvuminh estimatingtheeffectofdepressiononhivtransmissionriskbehaviorsamongpeoplewhoinjectdrugsinvietnamacausalapproach AT latkincarla estimatingtheeffectofdepressiononhivtransmissionriskbehaviorsamongpeoplewhoinjectdrugsinvietnamacausalapproach AT govivianf estimatingtheeffectofdepressiononhivtransmissionriskbehaviorsamongpeoplewhoinjectdrugsinvietnamacausalapproach |