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Disruption of fibronectin fibrillogenesis affects intraocular pressure (IOP) in BALB/cJ mice

Increased deposition of fibronectin fibrils containing EDA+fibronectin by TGFβ2 is thought to be involved in the reduction of aqueous humor outflow across the trabecular meshwork (TM) of the eye and the elevation in intraocular pressure (IOP) observed in primary open angle glaucoma (POAG). Using a f...

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Detalles Bibliográficos
Autores principales: Faralli, Jennifer A., Filla, Mark S., McDowell, Colleen M., Peters, Donna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444551/
https://www.ncbi.nlm.nih.gov/pubmed/32822410
http://dx.doi.org/10.1371/journal.pone.0237932