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CYP2C19 genotype-guided antiplatelet therapy: promises and pitfalls
Pharmacogenetic variants can alter the mechanism of action (pharmacodynamic gene variants) or kinetic processes such as absorption, distribution, metabolism and elimination (pharmacokinetic gene variants). Many initial successes in precision medicine occurred in the context of genes encoding the cyt...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Medicine Ltd
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444625/ https://www.ncbi.nlm.nih.gov/pubmed/32723143 http://dx.doi.org/10.2217/pgs-2020-0046 |